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Our Research Publications

PERC’s research is published in leading peer-reviewed journals, ensuring that our findings
contribute to the global knowledge base on public health and environmental issues.

Determinants of loss to follow-up among people living with HIV receiving antiretroviral therapy in a universal test and treat setting: A retrospective cohort study in Nepal

Objectives This study aims to assess the cumulative incidence and rate of loss to follow-up (LTFU) among people living with HIV (PLHIV) in Nepal who begin antiretroviral therapy (ART) early, as well as to identify factors associated with LTFU in the context of the universal test and treat approach. Study design Retrospective cohort study....

https://www.sciencedirect.com/science/article/pii/S2666535225000539

Shrestha A, Poudel L, Adhikari B, Bhandari S, Shrestha R, Kunwar RS, Pandey LR, KC MB, Wilson EC, Deuba K

Progress Toward the Elimination of Vertical HIV Transmission in Nepal: A Retrospective Cohort Study

Despite global advancements, pregnant women living with HIV in Nepal remain at risk for vertical transmission. This study examined demographic and clinical characteristics, antiretroviral therapy (ART) retention, and transmission outcomes among this population. A retrospective cohort analysis was conducted using data from Nepal’s national electr...

https://link.springer.com/article/10.1007/s10900-025-01474-6

Shrestha U, Pandey LR, KC MB, Mirzazadeh A, Deuba K

Leveraging DHIS2 Tracker for Breakthroughs in Public Health Research: A Pioneering Approach to HIV and TB Surveillance in Nepal.

DHIS2 has become a cornerstone for data collection and reporting in over 80 countries. This tool is pivotal in monitoring health program indicators, such as vaccination coverage, HIV testing/diagnosis, and tuberculosis (TB) treatment outcomes, aligning with national and global health strategies. However, traditional data reported through health ma...

https://community.dhis2.org/t/leveraging-dhis2-tracker-for-breakthroughs-in-public-health-research-a-pioneering-approach-to-hiv-and-tb-surveillance-in-nepal/57617

Deuba K

Burden of intimate partner violence, mental health issues, and help-seeking behaviors among women in Nepal

Background Intimate partner violence (IPV) is the most common form of violence, presenting a significant public health concern, especially for women and girls. Help-seeking can reduce future IPV and mitigate adverse health outcomes, including mental health issues. Objectives This study is the first national assessment on IPV, mental healt...

https://pmc.ncbi.nlm.nih.gov/articles/PMC11921001/

Kurvinen M, Ekström AM, Deuba K

Multilevel determinants of antiretroviral therapy initiation and retention in the test-and-treat era of Nepal: a qualitative study

BMC Health Serv Res. 2024 Aug 13;24(1):927. Abstract Background The transition to the “test-and-treat” policy in Nepal in 2017, coupled with the rapid initiation of antiretroviral therapy (ART) in 2020, necessitates an in-depth understanding of factors influencing ART initiation and retention. This study investigates these factors fr...

https://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-024-11311-6

Shrestha A, Poudel L, Shrestha S, Jha N, Kuikel BS, Shakya P, Kunwar RS, Pandey LR, KC MB, Wilson EC, Deuba K

Perceptions on violence against women and its impacts on mental health and response mechanisms among community-based stakeholders: a qualitative study from Nepal.

BMC Womens Health. 2024 Apr 24;24(1):258 Abstract Background: Violence against women (VAW) is a significant public health problem. With the emergence of the COVID-19 pandemic, the frequency and severity of VAW has escalated globally. Approximately one in four women in Nepal have been exposed to either physical, psychological, and/or sex...

https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-024-03064-5

Shrestha R, Sapkota D, Sarraf RR, Mehra D, Ekström AM, Deuba K.

Assessing the Nepalese health system’s readiness to manage gender-based violence and deliver psychosocial counselling

Abstract Violence against women (VAW), particularly intimate partner violence (IPV) or domestic violence, is a major public health issue, garnering more attention globally post-coronavirus disease 2019 (COVID-19) lockdown. Health providers often represent the first point of contact for IPV victims. Thus, health systems and health providers ...

https://academic.oup.com/heapol/article/39/2/198/7595865

Deuba K, Shrestha R, Koju R, Jha V, Lamichhane A, Mehra D, Ekström A

High Interest in the Use of mHealth Platform for HIV Prevention among Men Who Have Sex with Men in Nepal.

 J COMMUNITY HEALTH. 2024:1-13. PMID: 38281283, DOI: 10.1007/s10900-024-01324-x Abstract Mobile technology growth in Nepal offers promising opportunities for using mobile health (mHealth) interventions to facilitate HIV prevention efforts. However, little is known about access and utilization of communication technology and their w...

https://link.springer.com/article/10.1007/s10900-024-01324-x

Gautam K, Paudel K, Ahmed A, Dhakal M, Wickersham J, Poudel K, Pagoto S, Acharya B, Deuba K, Valente P, Shrestha R.

The impact of border crossing and imprisonment on injection practices and risk of HIV and hepatitis C infection among men who inject drugs in Nepal.

International Journal of Drug Policy. September 2023. Volume 119, 104145. Abstract Background In Nepal, personal drug use is criminalized and among people who inject drugs (PWID), the majority of whom are men, movement across the border with India for drug procurement and use is common. Using a risk environment approach, this study examin...

https://www.sciencedirect.com/science/article/pii/S0955395923001925

Zaccheo SK, Marrone G, Pandey LR, Deuba K

Disease Burden Attributed to Drug use in the Nordic Countries: a Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2019

Abstract The Nordic countries share similarities in many social and welfare domains, but drug policies have varied over time and between countries. We wanted to compare differences in mortality and disease burden attributed to drug use over time. Using results from the Global Burden of Disease (GBD) study, we extracted age-standardized estimate...

https://link.springer.com/article/10.1007/s11469-023-01131-w

GBD 2019 Nordic Drug Use Collaborators

Feasibility and Effectiveness of an Intervention to Reduce Intimate Partner Violence and Psychological Distress Among Women in Nepal: Protocol for the Domestic Violence Intervention (DeVI) Cluster-Randomized Trial.

JMIR Res Protoc. 2023 Aug 15:12:e45917. Abstract Background: Intimate partner violence (IPV) disproportionately affects people in low-and middle-income countries (LMICs), such as Nepal. Women experiencing IPV are at higher risk of developing depression, anxiety, and posttraumatic stress disorder. The shortage of trained frontline health...

https://www.researchprotocols.org/2023/1/e45917/

Shrestha R, Sapkota D, Mehra D, Ekström AM, Deuba K.

Prevalence of viral load suppression and acquired drug resistance among people living with HIV in Nepal: a nationally representative surveillance study.

J GLOB ANTIMICROB RESIST. 2023;35:122-127. PMID: 37709138, ABSTRACT Objectives This is the first nationally representative study to estimate the prevalence of viral load (VL) suppression and acquired HIV drug resistance (ADR) among people living with HIV (PLHIV) in Nepal. Methods A cross-sectional study recruited 1418 PLHIV fr...

https://www.sciencedirect.com/science/article/pii/S2213716523001522

Deuba K, Panta G, Rajbhandari R, Kunwar R, Pokhrel T, Pandey L, Changsom D, Saeng-Aroon S, Thakur S

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