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Designing Innovative Interventions to End the AIDS Epidemic
PERC Nepal is actively contributing to ending the AIDS epidemic by designing and implementing innovative programs and interventions. These efforts address the numerous challenges faced by populations affected by HIV. The PERC team has been deeply involved in assessing the public health burden, from psychosocial and mental health issues to drug resistance, among key populations and people living with HIV. In addition to assessment, the team evaluates existing programs and interventions targeting key and vulnerable populations. This evaluation aims to modify or introduce highly effective interventions that align with achieving global targets to end AIDS and viral hepatitis. The focus also extends to measuring the burden of common, curable sexually transmitted infections (STIs) such as syphilis and gonorrhea among key populations. PERC supports the design and implementation of targeted programs to address these burdens effectively. Below are some notable projects and publications from the PERC team that highlight their contributions to addressing these critical health issues.
Pioneering Digital Transformation: From Paper-Based to Tablet-Based HIV Surveillance in Nepal
Biological and Behavioral Surveillance (BBS) surveys are essential for tracking key indicators among populations at higher risk of HIV, including people who inject drugs, men who have sex with men, transgender individuals, se...
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Unveiling the Hidden Challenges: Psychosocial Health, Service Access, and HIV Risk Among Sexual and Gender Minorities in Nepal
Dr. Keshab Deuba, the Senior Health Advisor at PERC, received funding in 2009/2010 through the Netherlands Development Organization (SNV) and the Social Inclusion Research Fund (SIRF), Nepal, supported by the Norwegian Embass...
Read MoreDeterminants of loss to follow-up among people living with HIV receiving antiretroviral therapy in a universal test and treat setting: A retrospective cohort study in Nepal
Objectives This study aims to assess the cumulative incidence and rate of loss to follow-up (LTFU) among people living with HIV (PLHIV) in Nepal who begin antiretroviral therapy (ART) early, as well as to identify factors associated with LTFU in the context of the universal test and treat approach. Study design Retrospective cohort study....
https://www.sciencedirect.com/science/article/pii/S2666535225000539Progress Toward the Elimination of Vertical HIV Transmission in Nepal: A Retrospective Cohort Study
Despite global advancements, pregnant women living with HIV in Nepal remain at risk for vertical transmission. This study examined demographic and clinical characteristics, antiretroviral therapy (ART) retention, and transmission outcomes among this population. A retrospective cohort analysis was conducted using data from Nepal’s national electr...
https://link.springer.com/article/10.1007/s10900-025-01474-6Disease Burden Attributed to Drug use in the Nordic Countries: a Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2019
Abstract The Nordic countries share similarities in many social and welfare domains, but drug policies have varied over time and between countries. We wanted to compare differences in mortality and disease burden attributed to drug use over time. Using results from the Global Burden of Disease (GBD) study, we extracted age-standardized estimate...
https://link.springer.com/article/10.1007/s11469-023-01131-wSurvival on antiretroviral treatment among adult HIV-infected patients in Nepal: a retrospective cohort study in Far-western Region, 2006- 2011.
BMC Infectious Diseases. December 2013
http://www.ncbi.nlm.nih.gov/pubmed/24369908Prevalence of HIV, Hepatitis C and its related risk behaviours among women who inject drugs in the Kathmandu Valley, Nepal: a cross-sectional study.
Adv Infect Dis. 2021 Jan-Dec; 8: 20499361211062107 Abstract Background: People who inject drugs (PWID) are at great risk of HIV and Hepatitis C Virus (HCV). In order to properly design interventions and develop programmes for women who inject drugs, this study assessed the prevalence of HIV, Hepatitis B, Hepatitis C, and syphilis and its...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8646840/Prevalence of viral load suppression and acquired drug resistance among people living with HIV in Nepal: a nationally representative surveillance study.
J GLOB ANTIMICROB RESIST. 2023;35:122-127. PMID: 37709138, ABSTRACT Objectives This is the first nationally representative study to estimate the prevalence of viral load (VL) suppression and acquired HIV drug resistance (ADR) among people living with HIV (PLHIV) in Nepal. Methods A cross-sectional study recruited 1418 PLHIV fr...
https://www.sciencedirect.com/science/article/pii/S2213716523001522High Interest in the Use of mHealth Platform for HIV Prevention among Men Who Have Sex with Men in Nepal.
J COMMUNITY HEALTH. 2024:1-13. PMID: 38281283, DOI: 10.1007/s10900-024-01324-x Abstract Mobile technology growth in Nepal offers promising opportunities for using mobile health (mHealth) interventions to facilitate HIV prevention efforts. However, little is known about access and utilization of communication technology and their w...
https://link.springer.com/article/10.1007/s10900-024-01324-xTrends and determinants of HIV transmission among men who inject drugs in the Pokhara Valley, Nepal: analysis of cross-sectional studies.
BMC Public Health. February 2021. Abstract Background HIV is a major public health issue around the world, especially in developing countries. Although the overall prevalence of HIV in Nepal is relatively low, there are specific sub-populations where the prevalence is far higher than the national average. One of these sub-groups is ...
https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-021-10331-9Why don’t key populations access HIV testing and counselling centres in Nepal? Findings based on national surveillance survey.
Abstract Objectives To assess the demographic, behavioural, psychosocial and structural factors associated with non-utilisation of HIV testing and counselling (HTC) services by female sex workers (FSWs) and men who have sex with men/transgender (MSM/TG). Methods This study involved a cross-sectional design. We used the national sur...
http://bmjopen.bmj.com/content/7/12/e017408Condom use behaviour among people living with HIV: a seven-country community-based participatory research in the Asia-Pacific region.
Abstract Objectives: We examined the prevalence of inconsistent condom use and its correlates among people living with HIV (PLHIV) in the Asia-Pacific region. Methods: Between 1 October 2012 and 31 May 2013, a total of 7843 PLHIV aged 18-50 years were recruited using targeted and venue-based sampling in Bangladesh, Indonesia, Lao P...
http://sti.bmj.com/content/early/2017/11/08/sextrans-2017-053263
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